The Harlequin sign

The "harlequin" sign and congenital Horner's syndrome.

When trying to establish the likely anatomical site (preganglionic or postganglionic) of a lesion causing congenital Horner's syndrome, the distribution of facial flushing (the "harlequin" sign), may be seen. In babies and young children, facial flushing is a relatively simple clinical sign to demonstrate, compared with facial sweating. In unilateral facial flushing the areas that do not flush ...

Harlequin ichthyosis (or harlequin fetus)

The pat ient was a female neonate bor n prematurely on 36 weeks of gestation by normal vaginal delivery. During pregnancy, mother had no history of fever, drug use or x-ray exposure. The mother was gravida 2 and had no history of abortion. Her first baby was well. On physical examination, the skin was markedly thickened, hard and hyperkeratotic with deep crevices running transversely and vertic...

Internal carotid artery dissection and asymmetrical facial flushing: the Harlequin sign.

A 47-year-old woman presented to her primary care physician (PCP) with severe left-sided headache localized in the retrobulbar and temporal region. The PCP suspected migraine and prescribed a nonsteroidal anti-inflammatory drug. But despite analgesic treatment, her headache continued , and she returned to her PCP 2 weeks later. At this visit, the PCP noticed new anisocoria with a miotic pupil o...

Harlequin Syndrome

Harlequin foetus.